| Title | Year | Genre |
|---|---|---|
| Senshasen | 1992 | Action |
| Senshasen III VS-Bowler | 1996 | Action |
| SFXVI | 1998 | Fighting |
| Shanghai | 1987 | Puzzle |
| Shangrlia | 1991 | Adventure |
| Shangrlia 2 | 1993 | Strategy |
| Shangrlia 2 Special | 1993 | Software |
| Shiken Ni Denai Maison | ???? | Adventure |
| Shiken Ni Deru Urusei Yatsura Part 1 | 1989 | Adventure |
| Shikousakugo | ???? | Puzzle |
| Shimai Mahjongg | 1994 | Puzzle |
| Shinkeisuijaku Pro 68K | 1989 | Puzzle |
| Shinsetsu! Momotaro Game | ???? | Arcade |
| Shoot Range | 1992 | Strategy |
| Shooting 68K | 1991 | Shooter |
| Shooting Passion | 2000 | Shooter |
| Shouten | ???? | Arcade |
| Shuffle Puck Cafe | ???? | Arcade |
| Signatory | 1991 | Adventure |
| Silent Moebius | ???? | Adventure |
| Silkroad - Legend of Gero | ???? | Arcade |
| Silkroad 2 | 1995 | Adventure |
| Silsteel | 1995 | Shooter |
| Silver Ball | 1989 | Arcade |
| Silver Crystal | ???? | Puzzle |
| Sim Ant | 1993 | Management |
| Sim City - Terrain Editor | 1990 | Software |
| Sim City | 1990 | Management |
| Sim Earth | ???? | Management |
| Sion | 1991 | Action |
| SION II | 1992 | Shooter |
| SION IV | ???? | Shooter |
| Slime Master | ???? | RPG |
| Slimyer | 1990 | Arcade |
| SMSX Moon Soldier | ???? | Fighting |
| Snell | 1991 | Adventure |
| Snow Na Kibun! | 1991 | Quiz |
| Soft De Hard Na Monogatari | 1988 | Adventure |
| Soft De Hard Na Monogatari II | 1988 | Adventure |
| Sol-Feace | 1990 | Shooter |
| Solitea | 1990 | Puzzle |
| Sonic Linker | 1993 | Puzzle |
| Sora no Fudousan | 2004 | Adventure |
| Sorcerian Sugoroku | 1990 | Board game |
| Soroete Pon | ???? | Puzzle |
| Sotsugyou Graduation | 1993 | Adventure |
| Souhou Blue Phoenix | 1994 | Shooter |
| Soukoban | ???? | Puzzle |
| Space Battle | 1989 | Shooter |
| Space Harrier | 1985 | Shooter |
